Ozone and Coronavirus

With the intense interest in COVID-19, people are looking for answers.  Sanitizing and disinfection methods are being extensively explored.  One effective method is ozone treatment of buildings.

Ozone has a 99% effectiveness when killing pathogens like the flu, SARS, and the coronavirus. We have seen many versions of coronavirus in the past, and this novel coronavirus known as COVID-19 is yet another coronavirus that will have similar vulnerabilities to the past coronaviruses.  There has been bovine coronaviruses and human coronaviruses that we have now successfully treated.

Looking more closely at CODID-19, we see that it has not been previously identified in humans.  The novel coronavirus (COVID-19), is substantially related to the SARS virus (COV-2).  According to the World Health Organization (WHO), coronaviruses are comprised of a large family of viruses that cause illnesses that include the common cold, the more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV), and the Severe Acute Respiratory Syndrome (SARS-CoV).  As you should understand, coronaviruses are not new to us, and sanitizing against these diseases is not new.

Here is how ozone kills a virus.  Viruses are extremely small, independent particles, built of crystals and macromolecules that multiply only within the host cell. The novel coronavirus is an “enveloped virus.”  Enveloped viruses are commonly more sensitive to physico-chemical challenges.  

The Effect of Ozone on Viruses

Previous studies show that 99% of viruses have been damaged or destroyed after just 30 seconds of exposure to ozone.  Ozone destroys viruses by diffusing through the protein coat into the nucleic acid core, resulting in damage to the viral RNA. At higher concentrations, ozone destroys the exterior protein shell by oxidation. 

When disinfecting large areas, ozone gas has been proven to kill the SARS coronavirus.  Because the structure of the new 2019-nCoV coronavirus is almost identical, it is somewhat safe to believe that it will also work on the new coronavirus. Currently, there are more than 17 scientific studies that prove ozone gas can destroy the SARS coronavirus.

Ozone generators are able to make ozone from normal air and are normally used as room disinfectants.

The antipathogenic effects of ozone have been substantiated for several decades. Its killing action upon bacteria, viruses, fungi, and in many species of protozoa, serve as the basis for its increasing use in disinfecting municipal water supplies in cities worldwide.

Typically, viruses are small, independent particles, built of crystals and macromolecules. Unlike bacteria, they multiply only within the host cell. Ozone destroys viruses by diffusing through the protein coat into the nucleic acid core, resulting in damage of the viral RNA. At higher concentrations, ozone destroys the capsid or exterior protein shell by oxidation.

Numerous families of viruses including poliovirus I and 2, human rotavruses, Norwalk virus, Parvoviruses, and Hepatitis A, B and non-A non-B are among many others that are susceptible to the virucidal actions of ozone.

Most research efforts on ozone's virucidal effects have centered upon ozone's propensity to break apart lipid molecules at sites of multiple bond configuration. Indeed, once the lipid envelope of the virus is fragmented, its DNA or RNA core cannot survive.

Non-enveloped viruses (Adenoviridae, Picornaviridae, namely poliovirus, Coxsachie, Echovirus, Rhinovirus, Hepatitis A and E, and Reoviridae (Rotavirus), have also begun to be studied. Viruses that do not have an envelope are called "naked viruses." They are constituted of a nucleic acid core (made of DNA or RNA) and a nucleic acid coat, or capsid, made of protein. Ozone, however, aside from its well-recognized action upon unsaturated lipids, can also interact with certain proteins and their constituents, namely amino acids. Indeed, when ozone comes in contact with capsid proteins, protein hydroxides and protein hydroxides and protein hydroperoxides are formed. Viruses have no protections against oxidative stress.

https://www.ncbi.nlm.nih.gov/books/NBK92445/

https://finance.yahoo.com/news/ozones-effectiveness-killing-sars-coronavirus-000000776.html

https://www.tandfonline.com/doi/full/10.1080/01919510902747969?src=recsys

https://www.thailandmedical.news/news/ozone-can-be-used-to-destroy-the-new-coronavirus-and-disinfect-areas